 SCIENTIFIC PROGRAM |
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With some 300 attendees expected, including leaders in the fields of immunology and hematology, HLDA9 will provide an exciting forum for discussing the current understanding of human cell differentiation molecules. Sessions will include: Structure and function of different families of leukocyte cell-surface molecules; B cell function and B cell subsets; Diagnostic and therapy using monoclonal antibodies; Proteomics of the immune system; New techniques in the generation and use of monoclonal antibodies. Data generated by the HLDA9 workshop studies, as well as the new CD molecules, will be presented at HLDA9.
See the list of confirmed keynote speakers below.
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Thursday 11 March
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8.00
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Registration
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l'Academia Foyer
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8.30
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Opening plenary session
Chairperson: Laurence Boumsell
Welcome to HLDA9
Pablo Engel
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Main Auditorium
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David Mason Memorial Lecture
Leukocyte surface molecules: history and the future
Heddy Zola
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Main Auditorium
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9.30
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Plenary session: Structure and function of cell-surface molecules
Chairperson: Vaclav Horejsi
CD300 – Ancient molecules regulating immune responses
Georgina Clark
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Main Auditorium
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10:30
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Coffee break
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l'Academia Foyer
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11:00
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Plenary session: Structure and function of cell-surface molecules
SLAM family cell surface receptors as microbial sensors
Cox Terhorst
TIM genes: A family of phosphatidylserine receptors
Gordon Freeman
CD94/NKG2 C-type lectin-like receptors
Miguel Lopez-Botet
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Main Auditorium
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13.30
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Lunch
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l'Academia Grounds
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15.00
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Special sessions
SLAM and SAP adaptor families in immune responses – I
Antibody therapy
Production, characterization, and validation of mAbs (EuroMAbNet) – I
Ectoenzymes and disease – I
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Main Auditorium
Room 8
Room 9
Room 10
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16.45
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Coffee break
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l'Academia Foyer
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17.15
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Special sessions
SLAM and SAP adaptor families in immune responses – II
Phenotyping of immunodeficiences
Production, characterization, and validation of mAbs (EuroMAbNet) – II
Ectoenzymes and disease – II
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Main Auditorium
Room 8
Room 9
Room 10
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21.00
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GALA DINNER
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Restaurant
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Friday 12 March
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8.00
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Plenary session: B cell differentiation and B cell subsets
Chairperson: Pablo Engel
Dissection of human B cell differentiation: how to build up an immunocompetent repertoire?
Menno van Zelm
New insights in mucosal immunoglobin class switching
Andrea Cerutti
A role of protein kinase N1 in quality control of germinal center B cells
Hitoshi Kikutani
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Main Auditorium
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10:30
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Coffee break
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l'Academia Foyer
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11:00
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Plenary session: Targeting B cells
Chairperson: Andrea Cerutti
Targeting pathogenic and regulatory B cells in autoimmune disease
Thomas F. Tedder
Microenvironmental interactions and clinical features in CLL: the lesson of CD49d
Valter Gattei
Ectoenzymes at the junction between innate and adaptive immunity
Fabio Malavasi
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Main Auditorium
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13.30
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Lunch
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l'Academia Grounds
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15.00
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Special sessions
B cell malignancies – I
Proteomics and genomics
B cell subsets and plasma cells
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Main Auditorium
Room 9
Room 10
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16.45
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Coffee break
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l'Academia Foyer
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17.15
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Special sessions
B cell malignancies – II
Dendritic cells / Receptors of the innate immune system
New cell surface molecules
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Main Auditorium
Room 8
Room 9
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Saturday 13 March
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8.00
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Plenary Session: Leukocyte Signaling
Chairperson: Hannes Stockinger
Genetic and functional interactions between polymorphic receptors and counter-receptors in the MHC and NK receptor families
John Trowsdale
The roles of membrane rafts in leukocyte biology
Vaclav Horejsi
Tetraspan-enriched microdomains: a functional unit in cell plasma membranes
Francisco Sanchez-Madrid
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Main Auditorium
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10:30
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Coffee Break
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l'Academia Foyer
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11:00
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Plenary Session: Immunome
Chairperson: Heddy Zola
The human surface proteome using antibody-based proteomics
Mathias Uhlén
Ultra-sensitive single molecule fluorescence imaging for detection of CD-antigen function in live immune cells
Hannes Stockinger
The New CD Molecules
Pablo Engel
HCDM: Perspective on future developments
Laurence Boumsell
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Main Auditorium
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* EuroMabNet is a recently created organization that promotes the development of new technologies in the generation of monoclonal antibodies by European academic laboratories. HLDA9 will host the first formal international meeting of this organization.
Keynote Speakers
Laurence Boumsell (France)
Andrea Cerutti (USA)
Georgina Clark (Australia)
Gordon Freeman (USA)
Valter Gattei (Italy)
Vaclav Horejsi (Czech Republic)
Hitoshi Kikutani (Japan)
Miguel Lopez-Botet (Spain)
Francisco Lozano (Spain)
Fabio Malavasi (Italy)
Francisco Sanchez-Madrid (Spain)
Hannes Stockinger (Austria)
Thomas F. Tedder (USA)
Cox Terhorst (USA)
John Trowsdale (UK)
Mathias Uhlen (Sweden)
Menno van Zelm (The Netherlands)
Heddy Zola (Australia)
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